Penn researchers believe new potential gene therapy for glioblastoma brain cancer offers ‘a lot of hope’ Glioblastoma has been deadly and hard to treat, but researchers say they’ve made progress with ...

Cutting-edge technology and multidisciplinary care offer hope for brain tumour patients, improving outcomes and quality of ...

As the most common malignant brain tumors, glioblastoma multiforme (GBM) was characterized by angiogenesis and tumor cells proliferation. Dual targeting to neovasculature and GBM cells could deliver ...

The result is from the first clinical trial with FG001 in patients with High Grade Glioma and is an open-label, single-center phase I trial involving 35 patients, and FG001 was administered ...

1 Introduction. Globally, the prevalence of glioma has been progressively increasing, and the five-year survival rate remains dismally low ().Gliomas are classified by the World Health Organization ...

Gliomas exhibit significant molecular and clinical heterogeneity, current bio-markers alone fail to capture the full complexity of glioma progression (Mathur et al., 2024). By leveraging machine ...

The findings highlight the complexities of glioblastoma tumors and may prove useful in developing treatment strategies, Yue said. "This heterogeneity of genetic mutations and aberrant oncogene ...

To explore the temporal relationship between depression and dementia, we extracted individual study data from included meta-analyses. To ensure completeness, we supplemented the electronic search of ...

Remote sensing images often suffer from substantial data loss due to factors such as thick cloud cover and sensor limitations. Existing methods for imputing missing values in remote sensing images ...

Eligible patients have recurrent BRAF-V600E mutant glioma (any grade) with measurable disease (by RANO 2.0), have a Karnofsky performance status > 70, and are able to undergo surgery. Leptomeningeal ...