The new study, funded in part by the National Institutes of Health and published June 18 in Cell Chemical Biology, showed ...

Researchers have developed a new toolkit for detecting trypanosome parasites in livestock, aiding efforts to monitor and ...

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for ...

A promising new treatment to combat "undruggable" cancers has been green-lit for a human trial in 2025. It's hoped the novel ...

A high-fiber plant-based diet (HFPBD) can be beneficial for patients with monoclonal gammopathy of undetermined significance ...

Viruses use translation initiation factors through their own RNA structures or cap structures ... the delicate structure of the ribosome is gradually being revealed. Numerous studies have found that ...

To date, several pathogenic mutations have been found within the tandem BRCA1 carboxyl-terminal (BRCT) domains that mediate BRCA1 interactions with proteins and DNA in response to DNA damage. Here, we ...

Ribosomal RNA is the major structural component of the ribosome ... and primed for RNA synthesis to begin. “We found a large conformational change in part of the polymerase called the (sigma) factor ...

the remaining ribose is found as a closed-ring or an open-ring sugar with a reactive C1′ aldehyde group. Using primary amine-based reagents that react with the aldehyde group, we uncovered evidence ...

Ribosomal RNA (rRNA) from all organisms undergoes post-transcriptional modifications that ... These methylations reside in highly conserved sites found within the peptidyl transferase center (Decatur ...

Fortunately, we finally obtained a pair of efficient primers and identified the best reaction conditions. The GC content of each unit of the ribosomal RNA sequence unit was analysed and found to be ...