Dong, Z., Li, Q., Guo, D., Shu, Y. and Polli, J.E. (2015) Synthesis and Evaluation of Bile Acid-Ribavirin Conjugates as Prodrugs to Target the Liver. Journal of ...

Following 12 weeks of treatment with 1200 mg/d ribavirin in 39 patients with body weight >75 kg, mean ± SD AUC 0−12h was 25.4 ± 7.1 μg·h/mL and mean ± SD C max was 2748 ± 818 ng/mL The ...

Ribavirin inhibits the replication of infectious bursal disease virus predominantly through depletion ... et al. Investigating the influence of ribavirin on human respiratory syncytial virus RNA ...

Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a purine analogue and a commonly used antiviral agent against both RNA and DNA viruses. With up to five suggested mechanisms of ...

For a subgroup of patients with FIB-4 greater than 3.25, no statistical difference was found in the rate of SVR12 between patients who received ribavirin (28/28) and those who did not (21/23) (P = ...

1 Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China; 2 Yinzhou District Center for Disease Control and Prevention, Ningbo, China; 3 Center for ...

Ribavirin for treating Crimean Congo haemorrhagic fever. ... (RSV) polymerase and inhibits the synthesis of viral genetic material has been identified, a finding that could ...

T-705 (favipiravir) is a new antiviral agent in advanced clinical development for influenza therapy. It is supposed to act as an alternative substrate for the viral polymerase, causing inhibition of ...

Ribavirin is used to treat hepatitis C but causes serious hemolytic anemia. The objective of the study was to develop a ribavirin prodrug to achieve liver-specific drug delivery and to reduce its ...