Leveraging its high accuracy and programmability, the CRISPR system emerges as a promising platform for advancing the identification of SNPs. In this study, we compared two type V CRISPR/Cas systems ...

In this study, we developed a robust CRISPR interference (CRISPRi) system to precisely modulate gene expression in the bacterium Rhizobium etli, the nitrogen-fixing symbiont of the common bean. The ...

Meghana Keshavan covers biotech and contributes to The Readout newsletter. Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your ...

In February, doctors treated the infant with a breakthrough and historic CRISPR gene editing therapy, making KJ the very first patient in the world to receive this kind of personalized treatment.

Forbes contributors publish independent expert analyses and insights. Juergen Eckhardt leads Bayer’s impact investment unit, Leaps by Bayer.

In KJ’s case, the nanoparticles specifically directed the therapy to the liver. Researchers used a CRISPR base editor to repair a typo in one baby’s gene, in this case changing an incorrect ...

为解决植物在干旱等渗透胁迫下的生存难题，研究人员通过过表达Rhizobium rhizogenes的A4-rolB基因，系统研究了其对拟南芥形态、ABA（脱落酸）水平、抗氧化能力（TAC）及水通道蛋白（PIPs）表达的影响。结果表明，rolB-OX植株通过提前激活ABA信号和抗氧化防御 ...

The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China ...

Contributed by Gary Ruvkun, January 4, 2019 (sent for review September 13, 2018; reviewed by Danielle A. Garsin and Emily R. Troemel) ...