In this study, we developed a robust CRISPR interference (CRISPRi) system to precisely modulate gene expression in the bacterium Rhizobium etli, the nitrogen-fixing symbiont of the common bean. The ...

在气候变化加剧的背景下，土壤微生物如何应对极端温度成为生态学研究的热点。三叶草根瘤菌(Rhizobium leguminosarum sv. trifolii, Rlt)作为重要的固氮共生体，其低温适应机制直接关系到高纬度地区农业生态系统的氮循环效率。然而，现有研究多聚焦于常温条件下的 ...

本研究针对黑龙江菜豆根瘤中分离的根瘤菌多样性展开系统研究，通过多基因序列分析（16S rRNA、recA-atpD）、全基因组平均核苷酸同源性（ANI）和数字DNA杂交（dDDH）技术，鉴定出两株新种Rhizobium binxianense sp. nov.（模式菌株BJ04T ）和Rhizobium mulingense sp. nov.（模式 ...

“How awesome is it that we’re at this point?” said Nessan Bermingham, who co-founded and led Intellia, one of the first CRISPR companies, until 2017.

CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing ...

Forbes contributors publish independent expert analyses and insights. Juergen Eckhardt leads Bayer’s impact investment unit, Leaps by Bayer.

Meghana Keshavan covers biotech and contributes to The Readout newsletter. Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your ...

It has been described as a revolutionary technology — and won its inventors a Nobel Prize. CRISPR gene editing, often simply dubbed CRISPR, is a tool that allows scientists to precisely target ...

Nine-month-old KJ Muldoon recently underwent CRISPR-based gene editing by a team at Children's Hospital of Philadelphia and Penn Medicine in a historical medical breakthrough. The landmark study ...

More information: Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6 mediated gene editing in hematopoietic stem cells, Cell Reports Medicine (2025). DOI: 10.1016 ...

In KJ’s case, the nanoparticles specifically directed the therapy to the liver. Researchers used a CRISPR base editor to repair a typo in one baby’s gene, in this case changing an incorrect ...