B-cell depletion with unconjugated CD20 monoclonal antibody (mAb) is used to treat rheumatoid arthritis and other autoimmune ... in addition to reducing autoreactive T-cell activation through ...

Mass General Brigham researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery.

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion. ELK3 is a ...

we would want to make sure that they don’t have psoriatic arthritis instead of rheumatoid arthritis,” he says. Infection Germs sometimes enter a rash and cause an infection. Signs that a rash ...

While traditional treatments such as medication, injections, and surgeries have been widely used, they often only provide temporary relief and don’t address the root causes of the disease.