Introduction: We investigated the impact of rheumatoid arthritis (RA) associated cytokines and standard of care (SOC) RA therapeutics on immune checkpoint receptor (IR) expression on T cells to gain ...

autoantibodies against citrullinated IGF2BP1 are detected in patients with rheumatoid arthritis and positively correlate with disease severity.

Diet plays a pivotal role in influencing autoimmune diseases like multiple sclerosis (MS), inflammatory bowel disease, and ...

Background Rheumatoid arthritis (RA) and diabetes mellitus (DM) have common genetic risk factors, while molecular mechanisms behind this commonality have not been studied. Objectives To study ...

Conversely, T cell-derived TNF is protective during the induction phase of arthritis via ... Anti-tumour necrosis factor (TNF) therapy is widely used as a treatment for rheumatoid arthritis (RA) and ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

This review describes the IL-20 family of cytokines in rheumatoid arthritis (RA) and spondyloartrhitits (SpA ... IL-26 is produced in high amounts by myofibroblasts and IL-26 stimulation of monocytes ...

Clinical and Radiographic Outcomes of Four Different Treatment Strategies in Patients With Early Rheumatoid Arthritis (the Best Study): A Randomized, Controlled Trialfrom Arthritis & Rheumatism.

Rheumatoid arthritis (RA) is an inflammatory, autoimmune condition that affects not only joints but also organs, including eyes. While it can have painful and debilitating effects if left untreated, ...

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion. ELK3 is a ...

The FDA's approval is grounded in an evidence totality and comprehensive data package, which includes outcomes from a study.