Advanced hybrid controller could boost efficiency in biosynthetic production
This bacterial strain did not have a feedback loop but instead contained a second "input channel" to drive up the production ...
Nature4y
Transcription repression near the promoter region.
Molecules can interfere with RNA polymerase binding. An inactive repressor protein (blue) can become activated by another molecule (red circle). This active repressor can bind to a region near the ...
The Scientist4mon
Combining Bacterial Systems Offers a New Approach to Gene Regulation
Shelby is an Assistant Editor for The Scientist. She earned her PhD from West Virginia University in immunology and microbiology and completed an AAAS Mass Media fellowship. View Full Profile. Learn ...
Nature3y
Negative Transcription Regulation in Prokaryotes
How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...
Business Wire1mon
Scribe Therapeutics Presents Data on its Epigenetic Long-Term X-Repressor Technology at the 2025 Keystone Symposia on Precision Genome Engineering Conference
A high throughput screen of >30,000 diverse repressor domains from across the tree of life identifies repressor domains with unique structures that underpin enhanced epigenetic effector domain ...