High uric acid, a common concern due to modern lifestyles, can lead to gout and kidney stones. The body signals its presence through joint ... That's because water helps the kidneys filter and remove ...

Surgery may be required to treat some cases of gout. If there is a bacterial infection in the joint, the doctor may recommend surgery to wash the bacteria out of the joint. Surgery may also be ...

Surgical removal of the intradural lesion followed by pathological examination confirmed gouty tophi. The postoperative recovery was good, and the patient experienced substantial relief from pain and ...

These decrements in HRQOL vary across the spectrum of clinical phenotypes according to the presence and frequency of gout symptoms and signs. Patients with confirmed tophi and more frequent acute ...

Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric acid (monosodium urate) core, and the skin that covers them can become ...

a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to treat gout, today announced the U.S. Food and Drug ...

The impairment of HRQOL in patients with gout increases with the presence of tophi and the frequency of flares, even after adjusting for covariates. Gout symptoms are also associated with greater ...

Bone erosion in patients with gout and tophi was associated with tophi duration, drinking history, ulceration, and serum creatinine levels. Bone erosion in patients with gout and tophi was ...

Bone erosion in patients with gout and tophi was associated with tophi duration, drinking history, ulceration, and serum creatinine levels. Bone erosion in patients with gout and tophi was associated ...

The uric acid then passes through the kidneys and out of the body in the urine. Treating gout tophi requires a comprehensive plan. Your healthcare provider may prescribe medication and will also talk ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric ...