Mycoplasmas are successful pathogens that cause debilitating diseases in humans and various animal hosts. Despite the exceptionally streamlined genomes, mycoplasmas have evolved specific mechanisms to ...

The performance of AAV gene-therapy vectors is studied in machine-perfused human livers — and the presence of fatty liver disease makes a difference. Large-scale profiling of drug-induced ...

Understanding bacterial growth mechanisms can potentially help uncover novel drug targets that are crucial for maintaining cellular viability, particularly for bacterial pathogens. In this important ...

Researchers at the National Cancer Institute in Frederick, Md. have developed a new tool for editing and repairing bacterial DNA in vivo using *-mediated homologous recombination. Originally used with ...