The Discovery of New Members of the TNF Receptor and Ligand Families and Their Relationship to Osteoclasts and Bone Metabolism Binding of RANKL to RANK initiates a signaling cascade, which ...

Based on the hypothesis that the RANKL–RANK signalling pathway may be altered in the psoriatic joint, investigators analysed joint and bone tissues obtained from surgical samples. 56 They found ...

The VEGF-induced RANKL expression was decreased by the inhibition of both VEGF receptor 1 and 2 pathways. VEGF induced osteoclast differentiation from monocytes in the absence of RANKL. When monocytes ...

Cancer cells migrate to the bone surface from the circulation, and once there, increase the production of RANKL, which promotes bone resorption by osteoclasts. Bone destruction results in release ...

(2006) RANKL increase in compressed periodontal ligament cells from root resorption ... Smolen, J.S., Wagner, E.F. and Schett G. (2002) Osteoclasts are essential for TNF-alpha-mediated joint ...

I have reviewed the manuscript "Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast" with interest. The described findings are relevant and useful for daily ...

We are interested in molecular mechanisms underlying neural development, neuro-degeneration, and bone homeostasis. Although neural development, neurodegeneration, and bone homeostasis are three ...

1 Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China 2 Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, China Background: D ...

Mannens CCA; Hu L; Lonnerberg P; Schipper M; Reagor CC; Li X; He X; Barker RA; Sundstrom E; Posthuma D; Linnarsson S ...