因此,基因表达分析和代谢组学分析表明,虽然这两个基因拷贝具有冗余功能,但它们也具有特异性的分化功能,这是迄今为止所未知的。而且,由于它们的相似性,以及豆类对其他传统方法转化的抵抗力,使用CRISPR/Cas9(在豆类中很少使用)是必不可少的。
Scientists have linked roughly five percent of adult cancers to mutations in genes called FOCAD and TTC37. Another gene known ...
Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...
AZoLifeSciences on MSN10 小时
New CRISPR Tool Reveals Key Lymphoma Genes
This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.
They then deployed genome sequencing to analyse the genetic effects of these structural variations on cell survival. It ...
AZoLifeSciences on MSN10 小时
How Proteins Are Made: From DNA to Function
Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...
引言蛋白质复合物是执行细胞内复杂功能的关键分子,了解这些复合物的结构,不仅有助于揭示其功能机制,还能够为药物研发和疾病治疗提供新的思路。然而,随着研究的深入,蛋白质复合物的数量与复杂性急剧增加,如何快速、准确地比对和分析这些结构,成为了一个亟待解决的难题。传统的蛋白质复合物比对方法面临着计算量大、时 ...