Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

Not only will studies with these compounds provide opportunities to determine how the two states differ from each other, but they have already shown that RNA splicing is a target for cancer ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...

Here, our work pioneers a reversible approach to regulate RNA splicing within primary patient-derived cells by synthetic photoswitches. Our small molecule enables conditional real-time control at mRNA ...

Ultimately, Stoke Therapeutics is that classic “intriguing biotech” --hurdling to one of those proverbial “moments of truth” ...

The new study, funded in part by the National Institutes of Health and published June 18 in Cell Chemical Biology, showed ...

A new documentary about Phil Sharp dives deeper into his story, from his roots growing up with dyslexia and in severe poverty ...

Circular RNAs (circRNAs) are stable, ring-shaped molecules that play crucial roles in brain development, cognition, and long-term cellular regulation.

哈尔滨医科大学梁海海教授团队系统阐述了AS在肺癌、肺炎、哮喘、慢性阻塞性肺疾病、肺动脉高压和特发性肺纤维化等肺部疾病中的分子调控网络与临床价值。该综述深入探讨了AS事件作为复杂疾病治疗新靶点的重要意义，并全面解析了RNA剪接在肺部疾病中的前沿突破与诊 ...

A team of Indian American scientists led by Pallavi Gopal are working to learn more about the dynamics of a protein to help ...