All sizes of RNA are recovered at the same rate, eliminating the need for harmful chemicals such as phenol. Most cell types secrete exosomes, membrane vesicles ranging in size from 40 to 150 nm.

Basically, exosomes are like a cell’s text message—but instead of words or emojis, they contain data in the form of proteins, lipids, growth factors, and RNA. “In skincare, exosomes are ...

A fast and simple protocol for isolating exosomal RNA from exosomes previously purified using Norgen's Exosome Purification Kits, ultracentrifugation, size-exclusion chromatography, or most other ...

Exosomes are membrane-bound sacs measuring tens of nanometers in diameter. They are produced by cells and may contain molecules such as RNA and enzymes to communicate with other cells. Since the 2010s ...

The processing and degradation of RNA sequences is ubiquitous ... Despite the presence of multiple catalytic sites, the purified yeast exosome is almost entirely inactive. However, several ...

When RNA is released from EVs, it can activate a series of biological functions, such as affecting protein translation (including promoting and inhibiting effects) and changing gene expression ...

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the ...

A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house. A prime example is the RNA exosome. RNA ...

Here we show that exoribonuclease activities of Rrp6-associated RNA exosomes protect stable RNA species from TRAMP-mediated polyadenylation and degradation, and that each catalytic activity of the RNA ...