Sharma, Jiao and colleagues report glycosylation of small RNAs within exosomes and propose a glycosylation-dependent mechanism for RNA targeting into exosomes, which may influence intercellular ...

这篇研究揭示了细胞质DIS3作为独立于外泌体（exosome）的内切核糖核酸酶（endoribonuclease），通过其PIN结构域降解环状RNA（circRNA）的分子机制。研究通过生化分馏和重组蛋白实验证实，DIS3在细胞质中发挥独立功能，并影响多种内源性circRNA的稳定性，为circRNA代谢 ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 nucleotides longer than typical RNAs and are widely expressed in cells ...

Cell-free RNA (cfRNA) signatures in maternal blood at 16 weeks gestation can predict preterm birth (PTB) more than four months before delivery. Distinct cfRNA patterns differentiate PTB subtypes ...

When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury. But in neurological disorders such as ALS and spinal muscular atrophy, or following spinal ...