Warfarin is a commonly prescribed oral anticoagulant with narrow therapeutic index. It achieves anti-coagulating effects by interfering with the vitamin K cycle. Warfarin has two enantiomers, S(-) and ...

Designated as (R) or (S), ... (S)-enantiomer to (R). After some fiddling with reaction conditions, the researchers were able to reach an enantiomeric ratio of 94:6, nearly in quantitative yield.

10 Omeprazole is a racemic mixture of R-omeprazole and S-omeprazole, while esomeprazole, as its name implies, is isolated S-omeprazole. The S-omeprazole enantiomer was responsible for the drug’s ...

Most of the time, when a drug is asymmetric, one of its forms will be biologically active, and the other not. (The 50-50 mixture of enantiomers is called a racemate.) There are many examples of ...

(RTTNews) - iX Biopharma said that it will license to Seelos Therapeutics Inc (SEEL) its lead drug under development, Wafermine, a sublingual racemic ketamine wafer, and other products ...

In vivo testing has revealed that an enzyme called the 2-arylpropionyl-CoA epimerase converts (R)-ibuprofen into the active (S)-enantiomer. Due to the presence of this isomerise, ...

In fact, they only tested the unnatural enantiomer of the natural product because it was easy to make based on chemistry previously developed in Johnston’s lab (Proc. Natl. Acad. Sci. 2016, DOI ...

Esomeprazole is the more active, S-isomer or S-enantiomer of the PPI omeprazole (the R-isomer), which is marketed as Losec or Prilosec. Studies in laboratory rats have shown that the R-isomer is ...