Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

The information DNA contains is the instructions that the cell uses to make proteins. Proteins play a big part in determining the characteristics of specialised cells and whole organisms.

Sarika Kondra and her co-author's TSR-based method represents a major advancement in protein structure analysis, integrating ...

Protein is one of three essential macronutrients, alongside carbohydrates and fats. These are nutrients that the human body needs in relatively large quantities to function properly. Most official ...

In the subsequent years, DeepMind created the AlphaFold Protein Structure Database, which now includes over 200 million structures. Access to these protein structures opened the door to a deeper ...

Ribonucleic acid (RNA) molecules may be best known for their job ferrying the genetic information encoded in DNA to a cell's ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Pregnant or breastfeeding women, older adults, and people recovering from illness may also need more protein. Some data ...

Discover how a flexible protein can rearrange itself to multitask efficiently, revolutionizing medicine, agriculture, and ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Hyderabad: Scientists at the Centre for Cellular and Molecular Biology (CCMB) have recently made a significant discovery: ...

In today’s digital transformation era, scientific inquiry is increasingly guided by computational tools that uncover intricate biological mechanisms. Sarika Kondra, along with co-authors Feng Chen, ...