The prolyl isomerase PIN1 has been identified as a ... Protein phosphorylation is a key cellular signalling mechanism that induces changes in protein conformation 1,2. For example, the ...

针对肺腺癌(LUAD)靶向治疗和免疫治疗耐药难题，研究人员通过整合TCGA/GEO/HPA数据库、组织微阵列和体内外模型，揭示PIN1(peptidyl ...

The defects in molecular and cellular processes that constitute the triggers of specific pathologies are referred to as mechanisms of disease. Research in this area is vital for designing ...

Amazon has a pricing mechanism in place to evaluate competing offers since its marketplace hosts countless products from multiple sellers, including Amazon itself. The company said its systems ...

Molecular research has elucidated the mechanism controlling the developmental switch from fetal hemoglobin (HbF) to adult hemoglobin (HbA). BCL11A, the principal switch factor, which was ...

We are reaching alarming levels of AI insubordination. Flagrantly defying orders, OpenAI's latest o3 model sabotaged a shutdown mechanism to ensure that it would stay online. That's even after ...

Mercedes-Benz CEO Ola Kaellenius a day earlier proposed a similar mechanism whereby U.S. cars could be imported into Europe duty free in exchange for waivers on the same number of vehicles EU ...