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结果显示,唾液 mmp - 9、t - sod 和血清 mmp - 9 与大多数临床参数都呈正相关,就像它们之间有着紧密的 “联系”,一起影响着牙周炎的发展。 唾液 SIRT - 1 则和唾液 T - SOD 在治疗前后都有很强的正相关关系,这表明它们可能在牙周病环境中共同发挥作用。
mmp-9(基质金属蛋白酶 - 9,又称明胶酶 b)在细胞外基质(ecm)降解、正常组织更新和组织重塑中发挥重要作用。 研究表明,几乎所有类型的癌症中都存在 MMP-9 的过度表达,这证实了其在加速恶性病变中的作用,因此靶向 MMP-9 治疗癌症似乎是应对癌症不良病理的潜在策略。
Oncogene - MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion Skip to main content Thank you for visiting nature.com.
The promoter region of MMP-9 between −2500 and −2000 bp was found to be ... Zhi X, Feng J et al. miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 ...
MMP-9 expression was lower in co-treated MCF-7 cells relative to dandelion extract-treated cells. However, in MDA-MB-231 cells, MMP-9 expression did not significantly differ across treatment groups.
More information: Afiifah Machfuudzoh et al, At2-MMP is required for attenuation of cell proliferation during wound healing in incised Arabidopsis inflorescence stems, Plant And Cell Physiology ...
MMP-2 expression was measured by reverse transcription polymerase chain reaction (RT-PCR) and Western blot. Cell proliferation, apoptosis were examined by MTT, flow cytometry, respectively.
Researchers at University of Tsukuba have identified a gene, At2-MMP, that ... Prior research on this process has mainly concentrated on the initiation of cell proliferation.
A T/N fold-increase of 5.0 was used to discriminate between high (> 5.0) and low (< or = 5.0) T/N MMP-9 expression. High T/N MMP-9 RNA expression was associated with a significantly shorter ...
The firm’s pipeline comprises two preclinical-stage antibodies, the MMP-9-targeting CALY-001, and CALY-002, a humanized mAb targeting IL-15, which Calypso acquired from iDD biotech in 2013.