Here, the aim was to develop an ACPP sensitive to matrix metalloproteinase-2 and -9 (MMP-2/9) for nuclear imaging purposes. MMP-2/9 ACPPs and non-activatable cell-penetrating peptides (non-ACPP) were ...

SR9009 was found to exert REV-ERB–independent effects on proliferation, metabolism, and gene transcription in 2 different cell types depleted of REV-ERBs. Therefore, effects of these drugs cannot be ...

Background: Matrix metalloproteases (MMPs) are believed to be important in the pathogenesis of cigarette smoke-induced emphysema, but this hypothesis has only been proved in the mouse and its ...

Specific tissue expression of MMP-9 has been identified as a prognostic marker of healing of chronic ulcers. 10 A previous study has demonstrated high levels of both MMP-2 and MMP-9 in chronic VUs of ...