Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

The rise in potassium in the synaptic cleft was shown to increase calcium entry into the presynaptic neuron axon terminal when the postsynaptic neuron was stimulated, and enhanced the probability ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic ... reabsorbed back into the presynaptic neuron and ...

Interaction with the external world results in synaptic activity, and patterns in this activity, both presynaptic and postsynaptic, can lead to changes in the connections between individual ...

"Given the presynaptic role of synucleins in regulating ... "Consistent with this hypothesis, postsynaptic expression of tetanus toxin light chain, which cleaves synaptobrevin SNAREs, also blocks ...

Each of these levels covers a different scenario that can occur between the presynaptic and postsynaptic cell, such as spatial summation or coincidence potentiation. Using their knowledge of these ...

This enzyme degrades monoamine neurotransmitters after their reabsorption into the presynaptic neuron ... that prevents overstimulation of postsynaptic receptors. Neurotransmission can be enhanced ...

Dezhi Liao of the University of Minnesota, Minneapolis, noted that tau is enriched in axons and presynaptic terminals in healthy cells, but moves to postsynaptic structures in neurodegenerative ...

CPTX bridges presynaptic neurexins with postsynaptic AMPA receptors. This induced excitatory synapses in hippocampal neurons. Injected into 5xFAD mice, the chimera improved learning and memory. When ...