Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

In recent years, the 1954 Serotonin Theory of Depression and SSRIs have been thoroughly investigated by scientific ...

This explainer outlines how neurons and glial cells coordinate electrical and chemical signals to form complex brain networks ...

A new study published in Aging Cell has identified a promising molecule that may help reverse cognitive decline associated ...

Structurally, the activation of GPR158 enhances the lengths of both the AZ and the PSD. Functionally, GPR158 activation promotes short-term plasticity, such as PPF driven by presynaptic ...

While membrane-bound neprilysin reduced more amyloid, the secreted neprilysin better protected synapses, as measured by ELISAs for the presynaptic protein synaptophysin and the postsynaptic protein.

In the presence of normal global WO rates, asymptomatic LQTS patients showed higher global RI values. Conclusion The increased regional WO rate of [11 C]mHED in the lateral LV suggests an imbalance of ...

Expert Rev Neurother. 2013;13(9):1041-1059.

A variety of antidotes have been reported to treat SSRI-induced sexual dysfunction effectively; however, virtually all the data on these agents are derived from open case reports and case series ...

The evidence supporting this claim is compelling, demonstrating that SPNs uniquely integrate sparse input from variable stretches across the barrel cortex. The study would be of interest to basal ...