To make their model more realistic, they measured SIE in the presence of a high level of background synaptic activity, and used increasingly complex models of the postsynaptic neuron. Finally ...

Newly published research from Colorado State University answers fundamental questions about cellular connectivity in the brain that could be useful in the development of treatments for neurological ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic ... into the presynaptic neuron and restored inside a ...

This results in enough neurotransmitter being diffused across the synaptic cleft to trigger the impulse in the postsynaptic neuron. This process is called summation.

Neuron-glia coculture stained for neuronal Map2 (blue) and pre- and postsynaptic proteins vGlut1 (green) and Homer (red) respectively. Disclaimer: AAAS and EurekAlert! are not responsible for the ...