The polycomb repressive complex 2 (PRC2) comprises the methyltransferases Enhancer of Zeste Homologs 1 and 2 (EZH1/2), which tri-methylate Histone 3 on lysine 27 residues (H3K27me3) (Czermin et al, ...

The HUSH epigenetic repressor complex silences PML nuclear body-associated HSV-1 quiescent genomes. ... D. C. Bloom, The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome ...

Specifically, she identified one of the sequestered proteins was RNF2, the catalytic subunit of the polycomb repressor complex 1 (PRC1), which is an important transcriptional repressor. Additionally, ...

Polycomb repressive complex 2 (PRC2) ... Sengupta A, Wild B, et al. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell (2002) 111(2):197–208. doi: ...

Polycomb repressive complex (PRC) 1 regulates stem cell fate by mediating mono-ubiquitination of histone H2A at lysine 119. While canonical PRC1 is critical for hematopoietic stem and progenitor cell ...

Polycomb group (PcG) of proteins are a group of highly conserved epigenetic regulators involved in many biological functions, such as embryonic development, cell proliferation, and adult stem cell ...

The study (“The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression”) appears in Cancer Cell.

Moreover, a subset of CpG islands can also bind polycomb-group proteins, including the polycomb repressive complex 1 (PRC1) ... (2011) H3K27me3 is not required for recruitment of Polycomb repressor ...