However, the role of tumour-infiltrating B cells (TIBs) remains controversial. Here, we investigate the impact of TIBs and their interaction with T cells on HCC patient prognosis. Design Tissue ...

Follicular Dendritic Cell (FDC) Sarcoma: HV-CD often shows FDC proliferation, which can evolve into FDC sarcoma. ・ Plasma Cell Neoplasms: These can appear similar to PC-CD, especially when monotypic ...

Plasma Cell Neoplasms: These can appear similar to PC-CD, especially when monotypic plasma cell populations are present. ・ IgG4-related Disease (IgG4-RD): Frequently overlaps with PC-CD and iMCD ...

A Harvard study published in the journal Nature (2021) has revealed that chronic stress disrupts hair follicle stem cells ... ranging from platelet-rich plasma (PRP) injections to serums infused ...

The differential diagnosis for IgG4-RD includes conditions such as autoimmune pancreatitis, eosinophilic syndromes, multicentric Castleman disease, and plasma cell neoplasm, among others. Valencia OG, ...

Neoplastic cell morphology in peripheral blood (A) and bone marrow aspirate films (B) showing small- to medium-sized lymphoplasmacytic lymphocytes (May Grunwald Giemsa stain, 1000×). Bone marrow ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines ...

Several different cytokines are involved in inflammatory processes in the body, and if there are too many of them, they can negatively affect red blood cell production. Additionally, cancer-related ...

Here the authors show the presence of PD-L1 expressing regulatory plasma cells that can inhibit T cells in a murine model and in patients with sepsis. Plasma cell differentiation is governed by a ...

The researchers discovered that disease-scarred lung tissue abounds in plasma cells -- specialized immune cells that typically reside in bone marrow and produce antibodies. "What we found most ...