To test passenger strand cleavage and strand-dissociating ... The CXCR4* sequence is 5′-GUUUUCACAAAGCUAACACA-3′. Integrated DNA Technologies (IDT) synthesized all RNA molecules and modified ...

Specific DNA 18-mer sequences used for primer extensions are 5′−TGCATTTGTCACTGGAAC-3′ for the guide strand and 5′-GGTGAGGTTCCAGTGAC-3′ for the passenger strand of 22siRNA. For ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The other strand, known as the passenger strand ... the addition of single-carbon methyl groups to the transcribed DNA, leading to changes in gene organization that prevent further rounds of ...

First, they fabricated a universal single-strand DNA, as well as library of hundreds of short, single DNA strands called bricks. Each brick is composed of 24 nucleotides, including cytosine sites ...

For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life.

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to ...

"If this affects DNA strand separation, all protein interactions with DNA are also going to be affected," Marko said. "For example, the tendency for proteins to stick to specific sites on DNA and ...

On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand ...

DNA may embody the blueprint of life, but it could also be the stuff of future nanotechnologies. In a feat of molecular engineering, scientists recently designed a strand of DNA that can ...

Moderna’s mRNA COVID-19 vaccine does not alter human DNA or add a third strand to people’s DNA, as claimed in a video circulating on social media and viewed more than 400,000 times on Twitter.