The drug, Journavx by Vertex Pharmaceuticals, blocks pain signals to the brain, making it nonaddictive. By Gina Kolata The Food and Drug Administration approved a new medication Thursday to treat ...

1Department of Medicine, Division of Digestive and Liver Diseases, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York. 2Herbert Irving ...

The current Research Topic, “Molecular Crosstalk Between Endocrine Factors, Paracrine Signals, and the Immune System During Aging,” helps to bridge this gap by highlighting recent research findings at ...

aAbramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104-5156, United States This is the second in a Series of four papers about pancreatic cancer ...

The signals driving proliferation of committed progenitor cells are not known ... mutant stem cells expressing a degradation-resistant β-catenin in the pituitary promote cell non-autonomous ...

2 Collagen deposition can occur when normally quiescent fibroblasts are transformed into myofibroblasts that secrete collagen into the extracellular matrix in response to paracrine signaling molecules ...

Remarkably, when only mesenchyme cells surrounding postnatal GPs were killed, left bone growth was nevertheless reduced. GP signaling was impaired by altered paracrine signals from the knee joint, ...

Purpose: To investigate the joint influence by adipocytes and metabolic pressure on breast cancer cell expansion. Conclusion: These study results support the hypothesis that paracrine signals by ...