Department of Cardiology, Buddhist Tzu Chi General Hospital, Hualien 970, Taiwan School of Medicine, Tzu Chi University, Hualien 970, Taiwan Department of Physical Therapy, Graduate Institute of ...

Acetylcysteine （NAC，N - ...

The transcriptome sequencing showed that PD + Cur ameliorated CTD-ILD mainly by regulating aberrant immunoinflammation, which was further confirmed by proteomics that the PI3K/AKT/TGF-β pathway was a ...

Emerging evidence highlights the critical role of vitamin D3 in cellular aging and immune health, particularly through its ...

本研究针对肺纤维化(PF)治疗手段匮乏的现状，通过整合网络药理学、分子对接及体内外实验，揭示传统中药华仙方(HXF)通过 ...

LY294002（AbMole，M1925）是一种经典的、不可逆的PI3K（磷脂酰肌醇3激酶）抑制剂，LY294002通过阻断PI3K/Akt/mTOR信号通路，调节细胞 ...

Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

The Swiss drugmaker announced the global phase 3 SOLAR-1 trial evaluating the alpha-specific PI3K inhibitor codenamed BYL719 (alpelisib) has met the primary target and improved progression-free ...

HR-positive, HER2-negative breast cancer is already the most common subtype of breast cancer, comprising 70% of the breast cancers in the U.S., according to ASCO. About 40% of that population has ...

转录组学分析发现PI3K-Akt等造血相关通路的关键调控作用，为高原地区肿瘤患者的化疗支持治疗提供理论依据。 论文解读 在海拔超过3000米的高原地区，稀薄的空气导致氧气分压显著降低，这种慢性低氧环境对人体生理功能产生深远影响。尽管已有大量研究关注 ...