前列腺癌严重威胁男性健康，现有治疗手段存在局限。研究人员聚焦分支链氨基酸（BCAAs）及 BCAT2 在前列腺癌中的作用。发现 BCAT2 高表达与预后不良相关，其通过与 PCBP1 互作调节 PI3K/AKT 通路，影响细胞进程。该研究为前列腺癌诊疗提供新靶点和思路。

A deeper understanding of osteosarcoma , the most common primary malignant bone tumor affecting children and adolescents, is ...

A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is ...

Liver injury is an independent risk factor for multiple organ dysfunction and high mortality in patients with sepsis. However, the pathological mechanisms and therapeutic strategies for ...

编辑推荐：针对三阴性乳腺癌(TNBC)高转移性难题，中国科技大学团队发现抗氧化酶PRDX2通过激活PI3K/AKT/SP1信号轴促进FN1表达 ...

Ferroptosis is a novel form of programmed cell death characterized by iron-dependent accumulation of reactive oxygen species (ROS) and lipid peroxidation. The execution of ferroptosis is intricately ...

Zhejiang Provincial Key Lab for Chemical and Biological Processing Technology of Farm Product, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou ...

Ferroptosis, a recently identified non-apoptotic form of cell death, is characterized by the accumulation of reactive oxygen species (ROS), intracellular iron overload, and lipid peroxidation, ...