BMPER attenuated PI3K/AKT signaling and suppressed BMP4-driven smooth muscle activation in models of PAH. BMPER overexpression mitigated the vascular remodeling that characterizes pulmonary arterial ...

本研究针对乳腺癌高发病率与转移难题，揭示了γ-谷氨酰环化转移酶（GGCT）在调控乳腺癌细胞增殖、迁移和侵袭中的关键作用 ...

前列腺癌（PCa）是全球高发恶性肿瘤，但现有筛查和治疗手段存在局限。为解决NEIL3在前列腺癌中的作用机制问题，河北大学 ...

The FDA approved taletrectinib for ROS1-positive NSCLC. The agent shows efficacy for both new and pretreated cases, including ...

A new AI-driven multimodal fusion system accurately predicts survival outcomes in patients with unresectable liver cancer ...

Investigating tirzepatide's role in Alzheimer's reveals its potential to improve brain function and reduce inflammation, ...

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a leading cause of cancer-related deaths worldwide ...

传统观点认为，延胡索酸衍生物抑制CD8+ T细胞的功能，其天然代谢物的调控功能与机制则不清楚。延胡索酸对CD8+ T细胞的研究进展得益于近期江鹏实验室的工作。肿瘤微环境中的延胡索酸可直接抑制CD8+ T细胞的TCR ...