Furthermore, liver-specific Ube2f knockout attenuates steatosis and tumorigenesis induced by Pten loss in an mTORC1-dependent manner, suggesting a causal role of UBE2F in liver tumorigenesis. Finally, ...

For example, to run microarray analysis of human colon part: cd LXR_in_regeneration_and_tumorigenesis cd Human_Colon_CRC_Microarray conda activate base conda install -c conda-forge mamba mamba env ...

Interestingly, the anti-obesity drug orlistat or specific penetrating peptides can effectively attenuate AKT palmitoylation and activation by restricting PA synthesis or repressing AKT modification, ...

Gov. Andy Beshear announced Physician Care Coordination Consultants LLC (PC3 Health), a healthcare startup, is growing its Jefferson County operations with a $2.5 million investment to relocate ...

Ultra-low frequency (ULF) waves in the Pc3 range, with periods between 10–45 s, are routinely observed in Earth’s dayside magnetosphere. They are thought to originate in the foreshock, which extends ...

In 2019, Drs. Bruni and Nelson earned their doctor of medicine (MD) degrees as members of the inaugural cohort of the accelerated three-year medical education curriculum at CMSRU, referred to as the ...

The H3K14 acetyltransferase EP300 is required for the repression of BAZ2A‐target genes in PCa cells. Heatmap profiles of BAZ2A‐bound regions in PC3 cells and the corresponding signals of input, ...

Increasing evidence has linked claudins to signal transduction and tumorigenesis. The expression of claudins is frequently dysregulated in the context of neoplastic transformation. Studies have ...

Cancer is a disease characterized by uncontrolled cell proliferation, but the precise pathological mechanisms underlying tumorigenesis often remain to be elucidated. In recent years, condensates ...

Mechanisms of Tumorigenesis and Targeted Therapies Two of most commonly used prostate cancer cell lines LNCa P and PC3 are representative of prostatic adenocarcinoma and of Small Cell ...

The phrase ‘tumorigenesis’ refers to the initial formation of a tumor in the body. Over the last 50 years, the multiplicity of cancer has been demonstrated to be increasingly palpable via a ...

Find more information on the Altmetric Attention Score and how the score is calculated. The in vitro antiprostate cancer activity of lipophilic grape seed proanthocyanidin (LGSP) against the PC3 cell ...