中国农业科学院哈尔滨兽医研究所翁长江研究员团队2024年12月发表在Journal of Virology杂志上的一篇名为“Autophagy promotes p72 degradation and capsid disassembly ... 多泛素化的p72随后与自噬受体SQSTM1 / p62相互作用，导致其通过选择性自噬途径降解。这些发现揭示了p72通过自 ...

1 Department of Molecular Pathology and Biology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czechia 2 Institute of Organic Chemistry and Biochemistry, Czech Academy of ...

This month's cover highlights the article Local translatome sustains synaptic function in impaired Wallerian degeneration by Maria Paglione, Lukas Neukomm and colleagues. The image shows dissected ...

Although the mechanism by which ATG8ylation regulates the retromer remains unclear, the findings provide important insights with solid supporting evidence. ATG5 is one of the core autophagy proteins ...

There is a planned Crossref maintenance outage between Tuesday, 14 January 6:00 to 11:00 UTC. This impacts access to BibTeX and RIS files. This important study presents a series of results aimed at ...

We also demonstrate that the autophagic target SQSTM1/p62 is decreased in SOD1-G93A microglia after a short stimulation of P2X7, but increased after a sustained challenge. These effects are prevented ...