Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

The S1P receptor S1PR1 has a dominant role in immune-cell trafficking as a regulator of migration. However, other receptors, such as S1PR3 (in dendritic cells (DCs)) and S1PR5 (in natural killer ...