Oxidative stress contributes significantly ... Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.
Importantly, MTCH2 knockout cells showed an increase in mitochondrial oxidative function, which may explain the higher energy demand. Interestingly, this imbalance in energy metabolism and reductive ...
Furthermore, ML385, an NRF2 inhibitor, reversed these effects of EUG. The present study suggested that EUG exerted protective effects on pancreatic β cells in T1DM by attenuating apoptosis and ...
In this review, we integrate the latest data to elaborate on the interactions between oxidative stress and energy metabolism in various CVD, aiming to elucidate the higher incidence of CVD in ...
Ischemic stroke may promote HMGB1 lactylation by activating HIF-1, which can promote a shift in the mode of cellular energy acquisition from oxidative phosphorylation to glycolysis ... to exert ...
Precise instructions of God regarding the garments the priests should wear. The Ark of the Testimony, and the staves thereof, and the Mercy Seat (Ex. 39:35). The priests, on behalf of the worshiper, ...
and could possibly provide a means to decrease individual sensitivity to air pollution. As a consequence of recent research undertaken in a number of different countries, using a range of different ...
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It then very quickly forms a complex with the two components of the enzyme nitrogenase, which protects them from oxidative damage. In this process, the activated Shethna protein II binds the much ...
Pro-inflammatory macrophage activation is a hallmark example of how mitochondria serve as signaling organelles. Oxidative phosphorylation sharply decreases upon classical macrophage activation, as ...