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hLife编委风采 | 吕志民团队揭示肝癌酮体代谢重编程的新机制
酮体是由肝细胞通过氧化分解脂肪酸产生的一类中间代谢产物的统称,包括β-羟基丁酸、乙酰乙酸和丙酮。肝脏具有较强的合成酮体的酶系,但却缺乏利用酮体的能力。酮体从肝脏产生后通过血液循环进入脑、心脏和肌肉等器官,通过酮体分解(ketolysis)途径产生乙酰 ...
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