This article describes a point-of-care (POC) system—comprising a microfluidic, paper-based analytical device (μ-PAD) and a hand-held optical colorimeter—for quantifying the concentration of analytes ...

In target-based drug discovery, quantification of target engagement is required to build structure–activity relationships and develop a potent clinical candidate. Target engagement data also provides ...

Many patients self-present or are referred by primary care to the emergency department with chest pain because of the potential that they may be suffering an acute myocardial infarction, one of the ...

This valuable study combines massively parallel reporter assays and regression analysis to identify sequence features in untranslated regions contributing to the stability of in vitro transcribed mRNA ...

The Mouse Luminex Cytokine Assay represents a powerful and versatile tool for immune research. Its high throughput, sensitivity, and accuracy make it ideal for studying complex immune processes in ...

Thyroid-stimulating hormone (TSH) assay is considered a decisive diagnostic method for thyroid disorders. The lack of different TSH immunoassay standardization often leads to misdiagnosis of ...

HRD assays measure genotypic and/or phenotypic changes reflecting impairment of genes in the HRR pathway (causes) and genomic scarring/instability (ie, gLOH, TAI, LST, or consequences). 3 Each assay ...

Soil-free assays that induce water stress are routinely used to investigate drought responses in the plant Arabidopsis thaliana.Due to their ease of use, the research community often relies on ...

Fig. 1 Assessing the sensitivity and specificity of the LAMP assays. DNA plasmid containing the N gene of SARS-CoV-2 (2,000 cp/rxn) was used as template for LAMP amplification. a. Amplification plots ...

RT-PCR genotyping assays are suitable for high-throughput variant surveillance and could complement WGS, enabling larger scale testing for known variants and timelier results, with important ...

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