This article describes a point-of-care (POC) system—comprising a microfluidic, paper-based analytical device (μ-PAD) and a hand-held optical colorimeter—for quantifying the concentration of analytes ...

Instead, multigene panel–based sequencing with fewer genes (324-595 genes in currently available panels) and coding regions (0.8-2.4 Mb) is more often used to estimate TMB. 90,99-107 Panel ...

Tips for optimising and validating your multiplex qPCR assays Multiplex qPCR is a popular area of interest for many assay developers. Thanks to distinct reporter dyes, multiple reactions can be ...

At the 2025 ASCO Annual Meeting, Natera presented a pan-cancer study involving 392 patients and 2,600+ samples using Signatera Genome, a recently launched assay for clinical and research use.

In target-based drug discovery, quantification of target engagement is required to build structure–activity relationships and develop a potent clinical candidate. Target engagement data also provides ...

Objective The technology for the growth of human intestinal epithelial cells is rapidly progressing. An exciting possibility is that this system could serve as a platform for individualised medicine ...

Tempus is presenting new data on xM for TRM at the 2025 American Society of Clinical Oncology (ASCO®) Annual Meeting, highlighting the assay’s potential to help clinicians monitor response and ...

The LAMP assay specifically targets the H5 hemagglutinin gene of the avian influenza virus. This assay offers important advantages over traditional diagnostic methods, Kamel noted. It detects the ...

Multicancer early detection (MCED) assays use circulating tumor DNA, methylation patterns, RNA, and protein biomarkers to detect multiple cancer types early, potentially revolutionizing cancer ...

There was a very high correlation between the TB exclusion assay by flow cytometry, the PI (r 2 =0.9758) assay, and the Neubauer chamber (r 2 =0.8986) assay (Figure 5B). Interestingly, the assays ...