leading to the proposed nucleophilic aromatic substitution mechanism. We further clarify how 5NAA-A is tailored for its unprecedented and phylogenetically exceptional active site chemistry by ...

Moreover, combined kinetic and theoretical studies have further elucidated the mechanism of nucleophilic aromatic substitution as well as other electrophilic addition and substitution reactions ...

where S stands for substitution, N for nucleophilic, and the number denotes the molecularity of the reaction—1 for a unimolecular process and 2 for a bimolecular process. Figure 1. Mechanism of an S N ...