Structure and catalytic activity of the SAM-utilising ribozyme SAMURI. Hsuan-Ai Chen, Takumi Okuda, Ann-Kathrin Lenz, Carolin P. M. Scheitl, Hermann Schindelin & Claudia Höbartner. Published on 8 ...

Both ribozyme sequences were separated into two portions: the substrate part (LI_S_5F3T and OR_S_5F3T, Supplementary Table S4) and the enzymatic part ... 2017 The structure of a nucleolytic ribozyme ...

New ribozyme can make RNA molecules accessible for click chemistry in living cells. ScienceDaily . Retrieved April 11, 2025 from www.sciencedaily.com / releases / 2023 / 09 / 230905125007.htm ...

Article #19-14282: "An RNA polymerase ribozyme that synthesizes its own ancestor," by Katrina F. Tjhung, Maxim N. Shokhirev, David P. Horning, and Gerald F. Joyce.

Nucleolytic ribozymes are small RNAs that adopt compact folds capable of site-specific cleavage/ligation ... The structure of a nucleolytic ribozyme that employs a catalytic metal ion. Nat Chem Biol ...

The premise that some RNA sequences can catalyse and template their own replication - reciprocally synthesizing their own ‘+’ and ‘–’ strands - underpins current thinking about early genetic systems ...

The structure of the TS (formerly twister sister) ribozyme reveals details about its catalytic mechanism of nucleolytic self-cleavage using a hydrated magnesium ion, and illustrates key ...

The twister RNA is a recently discovered nucleolytic ribozyme that is present in both bacteria and eukarya. While its biological role remains unclear, crystal structure analyses and biochemical ...

For even the smallest ribozyme studied by the researchers, only 48 bases, there are 10,296 total single and double mutants. "With the help of a powerful DNA sequencer at OIST, we generated and then ...

We present a crystal structure at 2.3-Å resolution of the recently described nucleolytic ribozyme twister. The RNA adopts a previously uncharacterized compact fold based on a double-pseudoknot ...