S-nitrosylation is a post-translational modification of proteins by which thiol groups (SH groups) of cysteine residues are modified by nitric oxide to generate S-nitrosothiols (protein S ...

The process of NO-protein modifications—known as S-nitrosylation—was first described by Lipton and collaborators some 20 years ago. S-nitrosylation has important regulatory functions under ...

Lipton has been investigating a chemical process called S-nitrosylation, a post-translational modification whereby an NO-related molecule binds to sulfur atoms in proteins to produce ‘SNO’, altering ...

Central to the dysfunction is the aberrant modification of mitochondrial enzymes by S-nitrosylation, a chemical reaction where nitrogen and oxygen atoms bind to sulfur atoms on proteins.

Using cultured brain cells from mice and humans, the researchers first confirmed that excess NO leads to S-nitrosylation of CRTC1. They then discovered that this chemical modification prevented ...

S-Nitrosylation involves the transfer of a nitroso group to cysteine residues, resulting in the formation of S-nitrosothiols (SNO). This reversible post-translational modification dynamically ...

Subscribe for FREE Bayer said that aging in mice and humans both decrease a process known as S-nitrosylation, the modification of a specific brain proteins including CaMKII. “The current study now ...

A new study from researchers at Moffitt Cancer Center shows that blocking a chemical process called nitrosylation could make one of the most aggressive forms of melanoma more treatable. Their research ...

Sun Baolin from the University of Science and Technology of China (USTC) revealed the mechanism of transcriptional regulation via S-nitrosylation for vancomycin resistance in Staphylococcus aureus.

Using cultured brain cells from mice and humans, the researchers first confirmed that excess NO leads to S-nitrosylation of CRTC1. They then discovered that this chemical modification prevented ...