These melanomas often have overactive nitric oxide synthases (NOS), linked to worse outcomes. A study co-led by Premiexplored how nitrosylation, a modification caused by nitric oxide, affects the ...

These melanomas often have overactive nitric oxide synthases (NOS), linked to worse outcomes. A study co-led by Srivastava explored how nitrosylation, a modification caused by nitric oxide, affects ...

On Apr. 1, 2025, the last aircraft set for modification arrived at Eglin Air Force Base, Florida. The first three Vipers arrived at Eglin last year in April and are currently undergoing software ...

The experts found that this chemical modification, S-nitrosylation, interferes with normal brain cell function. In particular, it prevents brain cells from forming new connections, eventually causing ...

4A,B). Another important finding is that AMPK activity is regulated by NO-directed AMPKγ S-nitrosylation. Protein post-translational modifications, including phosphorylation, ubiquitination, glycation ...

S-Nitrosylation involves the transfer of a nitroso group to cysteine residues, resulting in the formation of S-nitrosothiols (SNO). This reversible post-translational modification dynamically ...

S-nitrosylation is a post-translational modification of proteins by which thiol groups (SH groups) of cysteine residues are modified by nitric oxide to generate S-nitrosothiols (protein S ...

Upon inflammation and changes in the cellular microenvironment, many extracellular soluble and membrane proteins undergo thiol modifications, particularly dithiol–disulfide exchange, ...

Abstract: S-Nitrosylation modification is one of the most important post-translational modifications; it plays a critical role in a vast variety of biological processes and is related to various ...