These results were validated using DETA-mediated nitrosylation induction and DTT as a reducing agent to break disulfide bonds between biotin and nitrosylated cysteines (Supplementary Fig. S6A–S6D).

On May 26th 2025, the Divertor Tokamak Test (DTT) project celebrated the completion of its first superconducting toroidal magnet. The milestone was marked at ASG Superconductors’ facility in La Spezia ...

DTT-UAP. Product GitHub Copilot Write better code with AI GitHub Models New Manage and compare prompts GitHub Advanced Security Find and fix vulnerabilities Actions Automate any workflow Codespaces ...

We use infrared spectroscopy to demonstrate the critical role that trace O2 plays in determining the products formed when a [2Fe2S] cluster protein reacts with nitric oxide (NO). The observed ...

Figure 1. The roles of cGMP and S-nitrosylation in NO-based signaling (A) and enzymatic protein denitrosylation mediated by the GSNOR and Trx systems (B).A, NOS synthesizes NO, which may activate sGC ...

In total, there are six DTT licences that allow the existence of 15 DTT channels in the country, out of which six are operated by Mediaset, five by Atresmedia and two each by Veo TV and Net TV. The ...

In DTT, every task is broken down into its component parts. The participant performs each component repeatedly until they master it, and only then do they move on to the next component.

Post-translational modifications are modifications that occur on a protein, catalysed by enzymes, after its translation by ribosomes is complete. Post-translational modification generally refers ...

As we get older, the level of nitric oxide in our bodies goes down, and this leads to a drop in S-nitrosylation. One of the proteins affected is CaMKII. When S-nitrosylation of CaMKII is reduced ...

When there’s not enough nitric oxide, the S-nitrosylation process doesn’t happen the way it’s supposed to. As a result, CaMKII doesn’t work as well, and our ability to learn and remember ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. This study shows a novel role for SCoR2 in regulating metabolic ...