The extracellular matrix protein fibronectin forms fibrils when in association with cells that exert tension. Cells apply enough force to stretch fibrils in vivo. Stretching of individual ...

ECs with increased CircOGDH expression were analyzed for changes in COL4A4 (collagen type IV alpha 4) levels, and in vitro coculture experiments were conducted to examine small extracellular ...

This study highlights lumican as a promising biomarker for predicting the onset and progression of diabetic nephropathy and reveals its close association with extracellular matrix remodeling, a ...

Recent research suggests that a large number of these proteins are either expressed differently or are found within EVs and can move between neurons and glial cells in different parts of the brain, ...

RNA-based technologies are a powerful molecular biology toolbox, empowering scientists to decipher the complexities of living ...

Extracellular vesicles (EVs) are nanoscale particles produced by cells and released ... basis for systematically elucidating their roles in the progression of mental disorders. In the state of mental ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Researchers have developed "infomorphic neurons" that learn independently, mimicking their biological counterparts more accurately than previous artificial neurons. A team of researchers from the ...

neurons and fat cells, niche factors such as pathogenic bacteria, extracellular matrix, hypoxia, acid, inflammation factors, as well as distal organs, individual behavior and comorbidities.

Researchers at the University of Rochester are exploring whether neurons can transmit light through their axons. If confirmed, this could reshape our understanding of brain function and open new paths ...

These findings highlight the importance of matrix component interactions in modulating detection sensitivity and show that these effects are critical in allowing clinically relevant detection levels ...