This resistance raised questions about their specialized function. Previous research has indicated the mitochondrial calcium uniporter’s (MCU) role in coupling neuron activity and mitochondrial ATP ...

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, memory, and social recognition. Led by Shannon Farris, assistant professor ...

Mitochondria are cytoplasmic organelles found ... most likely via protein S-cyanylation. A neuron-specific isoform of PGC-1α is regulated independently from other isoforms and is repressed ...

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, memory, and social recognition. Led by Shannon Farris, assistant professor ...

Mitochondria are essential organelles for neuronal function and cell survival. Besides the well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid biogenesis, regulation ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Mitochondrial dysfunction resulting from chronic oxidative stress has been linked with both altered neurotransmitter signaling and the inflammatory response. Hereinafter, we discuss mechanisms by ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

In a new study, scientists at Umeå University have found a way to break open the protective walls of pollen grains—one of the hardest biomaterials in the world—without damaging the inside ...

A study based on a survey of 50 adults linked poorer quality sleep with more depressive symptoms and respiratory issues in ...

Mitochondria are well known as the powerhouses of the cell. These crucial, energy generating organelles even have their own little genomes, and make their own proteins. Mutations in mitochondrial DNA ...