Development of novel influenza neuraminidase inhibitors is critical for preparedness against influenza outbreaks. Knowledge of the neuraminidase enzymatic mechanism and transition-state analogue ...

Influenza continues to pose a significant global health burden, with seasonal outbreaks causing substantial morbidity and ...

2022 年 5 月 12 日，武汉大学病毒学国家重点实验室周海兵教授、蓝柯教授、吴叔文副教授合作在国际学术期刊 Cell Insight 发表题为 “ Discovery of Oseltamivir-Based Novel PROTACs as Degraders Targeting Neuraminidase to Combat H1N1 Influenza Virus ” ...

在一项新的研究中，来自美国国家卫生研究院（National Institutes of Health, NIH）的研究人员发现了靶向流感病毒中一个难以发现区域的抗体，从而揭示了 ...

This article considers neuraminidase inhibitors, which are active against influenza virus and are crucial to planning for an influenza pandemic from a new influenza virus of any origin, including a ...

Cidara Therapeutics, a US biotech leveraging its Cloudbreak platform for next‑generation antivirals, saw its stock more than ...

Influenza continues to pose a significant global health burden, with seasonal outbreaks causing substantial morbidity and mortality. Current ...

The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: a prospective, observational study. Influenza Other Respir Viruses 2019;13: ...

InDevR Inc. announced product release of the first ever commercial reagent kit designed explicitly for assessment of neuraminidase (NA) in influenza vaccines. The new kit is poised to help improve ...

The study identifies four mutations in neuraminidase of human-like H5N1 influenza viruses that act synergistically to increase viral replication and induce moderate virulence in mammals, while ...

Influenza vaccines contain the viral surface proteins hemagglutinin and neuraminidase. While up to now, the constantly changing hemagglutinin has been considered the main protective antigen, and ...