Negative staining is a powerful preparative method for studying particulate specimens. In principle, the specimen is surrounded by heavy metal atoms that act as an electron barrier. Because the ...

In contrast to direct stains that bind to bacteria directly, a negative stain colors the background of a smear rather than the bacteria. These stains have negatively charged functional groups so they ...

The team demonstrated the technology's effectiveness using bacterial samples containing both Gram-positive and Gram-negative bacteria (Listeria innocua and Escherichia coli). The virtual staining ...