inhibition of necroptosis may be seen as providing a good therapeutic option in the acute phase of the disease. Inflammatory myopathies are systemic diseases which can affect the skin, lung ...

“Arsenite in combination with interferon as a cancer treatment promotes anti-cancer immunity, and necroptosis is known to be very good at promoting such immunity. The findings in this paper may ...

inhibition of necroptosis may be seen as providing a good therapeutic option in the acute phase of the disease. Inflammatory myopathies are systemic diseases which can affect the skin, lung ...

BUFFALO, NY- April 24, 2023 – A new editorial paper was published in Oncotarget's Volume 14 on April 10, 2023, entitled, “Tumor necroptosis promotes metastasis through modulating the interplay ...

Tumor cell deaths can benefit tumors. A paradox? Not at all. If, for example, a dying tumor cell undergoes necroptosis, it can release inflammatory factors that can enhance or diminish antitumor ...

"Can necroptosis be the trigger of inflammation in some cases and how is necroptosis regulated?" RIPK1 is a protein mainly known as an inducer of necroptosis. Researchers in the group of Manolis ...

Inhibiting necroptosis, a form of cell death, could yield a new treatment approach for chronic obstructive pulmonary disease (COPD), an inflammatory lung condition also known as emphysema ...

To address this issue, Prof. Nakano's group previously developed a biosensor for necroptosis called SMART (Sensor for MLKL activation by RIPK3 based on FRET). This biosensor is designed based on ...

The findings are published in Science Translational Medicine in an article titled, “Inhibition of an Alzheimer’s disease-associated form of necroptosis rescues neuronal death in a mouse model ...