资讯

生物通1 个月
《Nature Methods》Perturb-tracing 技术：解锁 3D 基因组调控因子筛选新密码
他们的研究成果发表在《Nature Methods》上，为 3D 基因组的研究开辟了新的道路。 研究人员开发了一种基于图像的高通量高内涵筛选平台 ——Perturb-tracing。该平台主要运用了三个关键技术：一是汇集式 CRISPR 筛选（pooled CRISPR screens），能够对众多候选基因进行大 ...
Genome-wide CRISPR screen identifies a novel target in NRAS-driven melanoma
Researchers at Novartis BioMedical Research in the US and Switzerland have identified a molecular target that may provide a ...
Nature2 天
CRISPR-Cas9 genome editing articles from across Nature Portfolio
yet traditional mutagenesis methods wrestle with genetic redundancy and a lack of specificity in gene targeting. Here the authors develop a scalable CRISPR system in tomato to edit multiple genes ...
The Scientist6 年
CRISPR Scientists Slam Methods Used on Gene-Edited Babies
View Full Profile. Learn about our Editorial Policies. In a move that has sparked outrage from scientists around the globe, researcher He Jiankui claimed to have used the gene-editing tool CRISPR to ...