This paper presents a multi-channel readout chip for high throughput single molecule sensing with solidstate nanopores. The readout IC achieves 1 MHz BW to capture the fast translocation signals ...

In this paper, a fully integrated high-sensitivity patch-clamp system is proposed for single-molecule deoxyribonucleic acid (DNA) analysis using a nanopore sensor. This system is composed of two main ...

Unnatural base pairs (UBPs) have been developed and used for a variety of in vitro applications as well as for the engineering of semisynthetic organisms (SSOs) that store and retrieve increased ...

Sample sheet is a csv file with the name of the sample and corresponding nanopore fastq.gz file on a single row with header sample and fastq. When Illumina fastq files are available for polishing or ...

Benchmarked base calling models for nanopore sequencing providing super high accuracy and improved RNA modification detection - novoalab/basecalling_models ...

Nanopore sequencing was performed with or without adaptive sampling for 72 h on a MinION Mk1b or GridION without reloading. Fast5 files and FASTQ files were collected for analysis. Data analysis and ...

Conformational changes of proteins are essential to their functions. Yet it remains challenging to measure the amplitudes and time scales of protein motions. Here we show that the cytolysin A (ClyA) ...

Zeolite nanopore model links crystal size to metal cluster migration and catalyst performance. Your friend's email. Your email. I would like to subscribe to Science X Newsletter. Learn more.