The NF2 gene encodes the production of a protein called merlin, which can clump together around nerve cells to form benign tumors. NF2 is a relatively uncommon condition, affecting roughly one of ...

To characterize the contributions of individual amino acids to the structure or function of a protein, researchers have adopted directed evolution approaches, which use iterated cycles of ...

This is the digital version of my master project's logbook that is created by using Streamlit Python package to document all the command lines and codes that I ran to do my project so that other ...

A mutated gene results in the loss of neurofibromin, which allows cells to grow uncontrollably. The NF2 gene is located on chromosome 22, and produces a protein called merlin (also called schwannomin) ...

Scientists have for the first time looked deep into the protein structure that may determine ... Moreover, mutations in the gene encoding RBP3 are associated with several eye diseases, including ...

The new model, called BaseFold, enables more reliable 3D structure predictions for larger and more complex proteins and, according to the company, is “poised to greatly accelerate AI-based drug ...

Credit: Photo realized Courtesy of DIFFERENT- Restaurant in the Darkness. Source IPC PAS, Grzegorz Krzyzewski Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing ...

While most studies focus on the entire protein structure, they often overlook the local structure of protein pockets which play a vital role in DTA due to their direct interaction with drugs. At the ...

MULAN uses the pre-trained base PLM and has the Structure Adapter – a module we introduce to incorporate the knowledge about the 3D protein structure. Our model uses ESM-2 architecture, initializing ...

To overcome these difficulties and visualize the architecture of a BLTP, we took a different approach and isolated the protein from the roundworm Caenorhabditis elegans. The structure showed that ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...